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  3. PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGAGGVGK, HEK293)

PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGAGGVGK, HEK293)

Cat. No.: HY-P701301
Handling Instructions

HLA-A*1101 is an important member of the MHC class I family and plays an important role in antigen presentation and immune surveillance. This complex is linked to the HLA-A*1101 allele and actively presents antigenic peptides to cytotoxic T lymphocytes, significantly promoting immune responses. PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGAGGVGK, HEK293) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with labeled tag and VVGAGGVGK peptide. PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGAGGVGK, HEK293), has molecular weight of 55-60 kDa & 14 kDa, respectively.

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Description

HLA-A*1101 is an important member of the MHC class I family and plays an important role in antigen presentation and immune surveillance. This complex is linked to the HLA-A*1101 allele and actively presents antigenic peptides to cytotoxic T lymphocytes, significantly promoting immune responses. PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGAGGVGK, HEK293) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with labeled tag and VVGAGGVGK peptide. PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGAGGVGK, HEK293), has molecular weight of 55-60 kDa & 14 kDa, respectively.

Background

The HLA-A*1101 is an integral member of the MHC class I family, playing a critical role in antigen presentation and immune surveillance. Characterized by its association with the HLA-A*1101 allele, this complex protein actively participates in presenting antigenic peptides to cytotoxic T lymphocytes, contributing significantly to the orchestration of immune responses. The PE labeling adds specificity to its antigen-binding capabilities, potentially influencing immune reactions in the context of cancers expressing KRAS antigens. As part of the MHC class I family, the HLA-A*1101 underscores its significance in advancing our understanding of immune processes and holds promise for applications in research focused on antigen presentation and immune system dynamics in the context of KRAS-associated malignancies.

Species

Human

Source

HEK293

Accession

Q5S3G3 (G25-T305)&P61769 (I21-M119)&VVGAGGVGK

Gene ID

3105&567

Synonyms
HLA-A*1101; B2M; KRAS; VVGAGGVGK
Molecular Weight

55-60 kDa&14 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGAGGVGK, HEK293) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
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PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGAGGVGK, HEK293)
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HY-P701301
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