PHKG1 Protein, Human (sf9, GST)

PHKG1, the catalytic subunit of phosphorylase b kinase (PHK), plays a pivotal role in the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and activating glycogen phosphorylase. Beyond its involvement in glycogen metabolism, PHKG1 exhibits in vitro phosphorylation activity towards various substrates such as PYGM, TNNI3, MAPT/TAU, GAP43, and NRGN/RC3, indicating its potential role in diverse cellular processes. PHKG1 Protein, Human (sf9, GST) is the recombinant human-derived PHKG1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of PHKG1 Protein, Human (sf9, GST) is 387 a.a., with molecular weight of ~65 kDa.

PHKG1, the catalytic subunit of phosphorylase b kinase (PHK), plays a pivotal role in the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and activating glycogen phosphorylase. Beyond its involvement in glycogen metabolism, PHKG1 exhibits in vitro phosphorylation activity towards various substrates such as PYGM, TNNI3, MAPT/TAU, GAP43, and NRGN/RC3, indicating its potential role in diverse cellular processes.

Human

Sf9 insect cells

N-GST

Q16816 (M1-Y387)

5260  [NCBI]

Approximately 65 kDa

Greater than 87% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.