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SAA4 Protein, Human (His)

Cat. No.: HY-P71277
COA Handling Instructions

SAA4 Protein, a notable acute phase reactant, plays a pivotal role in responding to physiological challenges. As a crucial apolipoprotein within the HDL complex, SAA4 regulates lipid metabolism and is integral to high-density lipoprotein dynamics. Elevated during acute phase responses, SAA4 underscores its significance in the adaptive mechanisms to diverse stressors. SAA4 Protein, Human (His) is the recombinant human-derived SAA4 protein, expressed by E. coli , with C-6*His labeled tag. The total length of SAA4 Protein, Human (His) is 112 a.a., with molecular weight of ~16 kDa.

For research use only. We do not sell to patients.

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50 μg $360 In-stock
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  • Biological Activity

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Description

SAA4 Protein, a notable acute phase reactant, plays a pivotal role in responding to physiological challenges. As a crucial apolipoprotein within the HDL complex, SAA4 regulates lipid metabolism and is integral to high-density lipoprotein dynamics. Elevated during acute phase responses, SAA4 underscores its significance in the adaptive mechanisms to diverse stressors. SAA4 Protein, Human (His) is the recombinant human-derived SAA4 protein, expressed by E. coli , with C-6*His labeled tag. The total length of SAA4 Protein, Human (His) is 112 a.a., with molecular weight of ~16 kDa.

Background

SAA4 Protein stands out as a prominent acute phase reactant, playing a pivotal role in the response to various physiological challenges. As a crucial apolipoprotein within the HDL complex, SAA4 contributes to the regulation of lipid metabolism and is integral to the dynamics of high-density lipoprotein. Its elevation during acute phase responses underscores its significance in the acute phase reactant network, reflecting its involvement in the body's adaptive mechanisms to diverse stressors.

Species

Human

Source

E. coli

Tag

C-6*His

Accession

P35542 (E19-Y130)

Gene ID
Molecular Construction
N-term
SAA4 (E19-Y130)
Accession # P35542
6*His
C-term
Synonyms
Serum Amyloid A-4 Protein; Constitutively Expressed Serum Amyloid A Protein; C-SAA; SAA4; CSAA
AA Sequence

ESWRSFFKEALQGVGDMGRAYWDIMISNHQNSNRYLYARGNYDAAQRGPGGVWAAKLISRSRVYLQGLIDCYLFGNSSTVLEDSKSNEKAEEWGRSGKDPDRFRPDGLPKKY

Molecular Weight

Approximately 16 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Appearance

Solution.

Formulation

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 200 mM NaCl, 0.5 mM EDTA, 20% Glycerol, pH 8.0.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

SAA4 Protein, Human (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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SAA4 Protein, Human (His)
Cat. No.:
HY-P71277
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