SLC30A8 Protein, Human (Sf9, His, MBP, FLAG)

The SLC30A8 protein is a proton-coupled zinc ion antiporter that coordinates essential zinc entry into pancreatic beta cell granules and significantly regulates insulin secretion. SLC30A8 Protein, Human (Sf9, His, MBP, FLAG) is the recombinant human-derived SLC30A8 protein, expressed by Sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag. The total length of SLC30A8 Protein, Human (Sf9, His, MBP, FLAG) is 368 a.a., .

The SLC30A8 protein serves as a proton-coupled zinc ion antiporter, orchestrating the crucial entry of zinc into the lumen of pancreatic beta cell secretory granules. This pivotal function plays a significant role in the regulation of insulin secretion. By actively participating in the transport of zinc ions within the secretory granules, SLC30A8 contributes to the intricate processes governing insulin release from pancreatic beta cells. The protein's unique role in mediating the proton-coupled transport of zinc underscores its importance in maintaining the delicate balance required for proper insulin regulation in response to physiological stimuli.

Human

Sf9 insect cells

N-MBP;C-Flag;N-8*His

Q8IWU4 (E2-D369)

169026

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.