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  3. TAS2R13 Protein, Human (Cell-Free, His)

TAS2R13 Protein, Human (Cell-Free, His)

Cat. No.: HY-P702468
Handling Instructions

TAS2R13 Protein, a receptor possibly involved in bitter taste perception, is linked to gustducin. It likely contributes to sensing the chemical composition of gastrointestinal content. Activation of this receptor stimulates alpha gustducin, triggers PLC-beta-2 activation, and results in the gating of TRPM5, indicating its role in bitter taste transduction and gustatory signaling pathways. TAS2R13 Protein, Human (Cell-Free, His) is the recombinant human-derived TAS2R13 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of TAS2R13 Protein, Human (Cell-Free, His) is 303 a.a., with molecular weight of 36.6 kDa.

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Description

TAS2R13 Protein, a receptor possibly involved in bitter taste perception, is linked to gustducin. It likely contributes to sensing the chemical composition of gastrointestinal content. Activation of this receptor stimulates alpha gustducin, triggers PLC-beta-2 activation, and results in the gating of TRPM5, indicating its role in bitter taste transduction and gustatory signaling pathways. TAS2R13 Protein, Human (Cell-Free, His) is the recombinant human-derived TAS2R13 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of TAS2R13 Protein, Human (Cell-Free, His) is 303 a.a., with molecular weight of 36.6 kDa.

Background

TAS2R13 functions as a receptor involved in the perception of bitterness and is linked to the gustducin signaling pathway. It is likely to play a role in sensing the chemical composition of gastrointestinal content. The activation of this receptor stimulates alpha gustducin, facilitating the activation of PLC-beta-2 and ultimately leading to the gating of TRPM5. This intricate signaling cascade suggests that TAS2R13 contributes to the complex mechanism of taste perception, particularly in the detection of bitter compounds, and may have implications in the regulation of gustatory responses in the gastrointestinal tract.

Species

Human

Source

E. coli Cell-free

Tag

N-10*His

Accession

Q9NYV9 (M1-R303)

Gene ID

50838

Molecular Construction
N-term
10*His
TAS2R13 (M1-R303)
Accession # Q9NYV9
C-term
Synonyms
Taste receptor type 2 member 13; Taste receptor family B member 3; TRB3
AA Sequence

MESALPSIFTLVIIAEFIIGNLSNGFIVLINCIDWVSKRELSSVDKLLIILAISRIGLIWEILVSWFLALHYLAIFVSGTGLRIMIFSWIVSNHFNLWLATIFSIFYLLKIASFSSPAFLYLKWRVNKVILMILLGTLVFLFLNLIQINMHIKDWLDRYERNTTWNFSMSDFETFSVSVKFTMTMFSLTPFTVAFISFLLLIFSLQKHLQKMQLNYKGHRDPRTKVHTNALKIVISFLLFYASFFLCVLISWISELYQNTVIYMLCETIGVFSPSSHSFLLILGNAKLRQAFLLVAAKVWAKR

Molecular Weight

36.6 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

TAS2R13 Protein, Human (Cell-Free, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
TAS2R13 Protein, Human (Cell-Free, His)
Cat. No.:
HY-P702468
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