YidC Protein, E.coli (Cell-Free, His)

The YidC protein is essential for insertion, folding, and formation of integral membrane protein complexes. It is involved in the integration of membrane proteins, both dependent and independent of the Sec translocase complex, including some lipoproteins. YidC Protein, E.coli (Cell-Free, His) is the recombinant E. coli-derived YidC protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of YidC Protein, E.coli (Cell-Free, His) is 548 a.a., with molecular weight of 63.0 kDa.

YidC Protein emerges as a critical player in the intricate processes governing the insertion, folding, and complex formation of integral membrane proteins within the cellular membrane. Its versatile role encompasses facilitating the integration of membrane proteins that rely on both Sec translocase-dependent and -independent pathways, extending its functional impact to a diverse range of cellular processes. Beyond mere insertion, YidC is instrumental in aiding the proper folding of multispanning membrane proteins, contributing to the intricate three-dimensional architecture essential for their functionality. Notably, YidC establishes interactions with the Sec translocase complex, forming a collaborative network with components like SecD. Its specific interaction with transmembrane segments during the integration process underscores its nuanced involvement in the meticulous orchestration of membrane protein biogenesis.

E.coli

E. coli Cell-free

N-10*His

A8A6G7 (M1-S548)

75205420

MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS

63.0 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.