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Results for "

(-)-JNJ-A07

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139602C
    (-)-JNJ-A07

    		Flavivirus Infection
    (-)-JNJ-A07 is a potent and selective DENV inhibitor with an EC50 value of 31 nM .
    (-)-<em>JNJ-A07</em>
  • HY-139602
    (+)-JNJ-A07

    		Flavivirus Dengue virus Virus Protease Infection
    (+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models .
    (+)-<em>JNJ-A07</em>

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