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" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-108039
    HE 3286

    NF-κB Metabolic Disease Inflammation/Immunology Neurological Disease
    HE 3286 is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. HE 3286 is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. HE 3286 freely penetrates the blood brain barrier in mice. HE 3286 can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis.