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Targets Recommended: CRISPR/Cas9

Results for "1207629-49-9" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-118250
    GSK2245035

    Toll-like Receptor (TLR) IFNAR TNF Receptor Inflammation/Immunology
    GSK2245035 is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 has pEC50s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 is used for the treatment of asthma.