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" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-P99110

    SHP643; DX-2930

    Ser/Thr Protease Inflammation/Immunology
    Lanadelumab (SHP643) is a humanized IgG1 monoclonal antibody against plasma kallikrein (pKal) with an Ki value of 0.12 nM. Lanadelumab inhibits both free and HMWK (high molecular weight kininogen)-bound pKal. Lanadelumab has the potential for the research of hereditary angioedema.