1. Search Result

Search Result

Results for "21919-05-1" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-13543

    CB 1954

    DNA Alkylator/Crosslinker Cancer
    Tretazicar (CB 1954), an antitumor prodrug, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1).