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3’-Azido-3’-deoxy-beta-L-adenosine

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  • HY-152601
    3’-Azido-3’-deoxy-beta-L-adenosine

    		Nucleoside Antimetabolite/Analog Others
    3’-Azido-3’-deoxy-beta-L-adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-beta-L-adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    3’-<em>Azido-3</em>’-<em>deoxy</em>-<em>beta-L-adenosine</em>

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