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Results for "

457081-03-7

" in MCE Product Catalog:
Cat. No. Product Name Target Research Areas
  • HY-14435
    Pyridone 6

    		JAK Cancer
    Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases.