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475488-23-4

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10252
    NVP-ADW742
    2 Publications Verification

    ADW742; GSK 552602A; ADW

    		 IGF-1R Insulin Receptor Apoptosis Endocrinology Cancer
    NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells .
    NVP-ADW742

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