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5’-Azido-5’-deoxy-2’-O-(2-methoxyethyl)-5-methyluridine

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-154386
    5’-Azido-5’-deoxy-2’-O-(2-methoxyethyl)-5-methyluridine

    		Nucleoside Antimetabolite/Analog Cancer
    5’-Azido-5’-deoxy-2’-O-(2-methoxyethyl)-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 5’-Azido-5’-deoxy-2’-O-(2-methoxyethyl)-5-methyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    5’-<em>Azido</em>-5’-<em>deoxy</em>-2’-O-(2-<em>methoxyethyl</em>)-5-<em>methyluridine</em>

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