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748810-28-8

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14183
    Vernakalant Hydrochloride
    3 Publications Verification

    RSD1235 hydrochloride

    		 Potassium Channel Cardiovascular Disease
    Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na + and atria-preferred K + channel blocker. IC50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.35±0.93 μM, 0.61±0.03 μM, and 1.63±0.09 μM for Kv1.5 channel wt, Kv1.5 channel I508F, Kv1.5 channel T479A, respectively.
    Vernakalant Hydrochloride
  • HY-14182
    Vernakalant

    RSD1235

    		 Potassium Channel Cardiovascular Disease
    Vernakalant(RSD-1235) is an investigational mixed ion channel blocker that can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more atrial-selective than available agents; in treatment of antiarrhythmic.
    Vernakalant

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