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Results for "874146-69-7" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-128784
    PK11007

    MDM-2/p53 Reactive Oxygen Species Cancer
    PK11007 is a mild thiol alkylator with anticancer activity. PK11007 stabilizes p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. PK11007 induces mutant p53 cancer cell death by increasing reactive oxygen species (ROS) levels.