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AChE/BACE1/GSK3β-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-151260
    AChE/BACE1/GSK3β-IN-1

    		Beta-secretase Cholinesterase (ChE) GSK-3 Neurological Disease
    AChE/BACE1/GSK3β-IN-1 is an orally active triple inhibitor of AChE/BACE1/GSK3β. AChE/BACE1/GSK3β-IN-1 has effective inhibitory activity against AChE, BACE1 and GSK3β with IC50 values of 1.0 μM, 20 μM and 15 μM, respectively. AChE/BACE1/GSK3β-IN-1 has good blood-brain barrier penetrability, suitable bioavailability. AChE/BACE1/GSK3β-IN-1 can be used for the research of Alzheimer's disease (AD) .
    <em>AChE/BACE1</em>/<em>GSK3β-IN-1</em>

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