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BChE-IN-20

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155368
    BChE-IN-20

    		Cholinesterase (ChE) Neurological Disease
    BChE-IN-20 (compound 7c) is a highly potent BChE-selective inhibitor and exhibits IC50s of 105 and 2.3 nM for eqBChE and hBChE, respectively. BChE-IN-20 inhibits P glycoprotein with IC50 of 0.27 μM. BChE-IN-20 is a promising template to improve design and development of BChE-selective ligands of pharmaceutical interest, including inhibitors and fluorogenic probes.
    <em>BChE-IN-20</em>

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