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Isoforms Recommended: ALK3
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Bmpr1a

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  • HY-P7484
    BMPR1A/ALK-3 Protein, Human (129a.a, HEK293, Fc-His)

    Bone morphogenetic protein receptor type-1a; ALK-3; SKR5; CD292; ACVRLK3; Bmpr-IA

    		 Human HEK293
    BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders. Human BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Human (129a.a, HEK293, Fc-His) is produced in HEK293 cells and has 129 amino acids (Q24-R152), with C-terminal Fc- and His-tags.
  • HY-P75594
    BMPR1A/ALK-3 Protein, Human (152a.a, HEK293, His)

    ALK-3; Bmpr­IA; Bone morphogenetic protein receptor type-1a; SKR5; CD292

    		 Human HEK293
    BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders. Human BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Human (152a.a, HEK293, His) is produced in HEK293 cells and has 152 amino acids (M1-R152), with a C-terminal His-tags.

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