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Results for "

FLT3/TrKA-IN-1

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Peptides

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-146749
    FLT3/TrKA-IN-1

    		FLT3 Trk Receptor Apoptosis Cancer
    FLT3/TrKA-IN-1 is a potent FLT3/TrKA dual kinase inhibitor with the IC50s of 43.8 nM, 97.2 nM, 92.5 nM and 23.6 nM for FLT3, FLT3-ITD, FLT3-TKD and TrKA, respectively. FLT3/TrKA-IN-1 induces cell cycle arrest at the G0/G1 phase as well as apoptosis and shows antiproliferative activity in vitro. FLT3/TrKA-IN-1 has the potential for the research of Acute myeloid leukemia (AML) [1].
    <em>FLT3</em>/<em>TrKA-IN-1</em>

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