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JAK-IN-27

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153702
    JAK-IN-27

    		JAK Cancer
    JAK-IN-27 (compound 1) is an orally active and potent JAKS family kinase inhibitor with IC50s of 3.0 nM (TYK2), 7.7 nM (JAK1), 629.6 nM (JAK3), respectively. JAK-IN-27 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC50=23.7 nM) .
    <em>JAK-IN-27</em>

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