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Results for "

Nek1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-144425
    BSc5367

    		Others Inflammation/Immunology
    BSc5367 is a potent Nek1 inhibitor with an IC50 of 11.5 nM. NIMA-related protein kinase Nek1 is crucially involved in cell cycle regulation, DNA repair and microtubule regulation and dysfunctions of Nek1 play key roles in amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD) and several types of radiotherapy resistant cancer [1].
    BSc5367
  • HY-103646
    CK7

    		CDK Others
    CK7, a Cdk2/9 inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367 [1].
    CK7
  • HY-122639
    ZINC05007751
    1 Publications Verification

    		 Others Cancer
    ZINC05007751 is a potent NIMA-related kinase NEK6 inhibitor with an IC50 of 3.4 μM. ZINC05007751 shows antiproliferative activity against a panel of human cancer cell lines, and displays a synergistic effect with Cisplatin and Paclitaxel in a BRCA2 mutated ovarian cancer cell line. ZINC05007751 is very selective against NEK1 and NEK6 with no significant activity was observed against NEK2, NEK7, and NEK9 [1].
    ZINC05007751
  • HY-RS09190
    NEK1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    NEK1 Human Pre-designed siRNA Set A contains three designed siRNAs for NEK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    NEK1 Human Pre-designed siRNA Set A
    NEK1 Human Pre-designed siRNA Set A

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