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PI3Kδ-IN-14

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155975
    PI3Kδ-IN-14

    		PI3K Inflammation/Immunology
    PI3Kδ-IN-14 (Compound (S)-29) is a selective PI3Kδ inhibitor (IC50: 0.8 nM, Kd: 84.8 nM). PI3Kδ-IN-14 binds to the ATP-binding site of the kinase domain of PI3Kδ. PI3Kδ-IN-14 has anti-inflammatory activity by inhibiting the PI3K/AKT pathway. PI3Kδ-IN-14 ameliorates acute lung injury (ALI) .
    <em>PI3Kδ-IN-14</em>

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