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TTBK1-IN-2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145313
    TTBK1-IN-2

    		Others Neurological Disease
    TTBK1-IN-2 (compound 29) is a potent Tau-Tubulin kinase (TTBK1) inhibitor with IC50s of 0.24 and 4.22 µM, respectively. TTBK1-IN-2 reveals good brain penetration in vivo and is able to reduce TDP-43 phosphorylation not only in cell cultures but also in the spinal cord of transgenic TDP-43 mice .
    <em>TTBK1-IN-2</em>

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