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Tnf

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P70800
    TNF-alpha/TNFSF2 protein, Rabbit
    1 Publications Verification

    Tumor Necrosis Factor; Cachectin; Tnf-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; Tnf-a; Tnf; TnfA; TnfSF2

    		 Rabbit E. coli
    Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF-alpha/TNFSF2 protein, Rabbit is a recombinant protein consisting of 158 amino acids (V78-L235) and is produced in E. coli.

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