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Results for "

Tusamitamab

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

2

Inhibitory Antibodies

Cat. No. Product Name Target Research Area
  • HY-P99054

    Inhibitory Antibodies Cancer
    Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative) .
  • HY-P99542

    SAR-408701; HuMAb2-3-SPDB-DM4

    Antibody-Drug Conjugates (ADCs) Microtubule/Tubulin Cancer
    Tusamitamab ravtansine (SAR-408701) is a targeted ADC against tumor cells expressing CEACAM5, composed of a humanized anti-CEACAM5 monoclonal antibody covalently linked to the potent cytotoxic agent, maytansinoid DM4 (HY-12454), via a cleavable linker. Tusamitamab ravtansine has an average drug-to-antibody ratio (DAR) of 3.8 .

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