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Winrevair

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

2

Inhibitory Antibodies

Cat. No. Product Name Target Research Area
  • HY-P99590A

    Inhibitory Antibodies Cardiovascular Disease
    Sotatercept (mIgG2a) has direct cardioprotective actions, which reduces right ventricular (RV) remodeling and improves function in a pulmonary artery banding (PAB) mouse model .
  • HY-P99590

    ACE-011

    TGF-β Receptor Inflammation/Immunology Cancer
    Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions .

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