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Results for "

intracytoplasmic

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147561
    ALPK1-IN-1

    		NF-κB Infection Inflammation/Immunology
    ALPK1-IN-1 (Compound A001) is a potent inhibitor of alpha-kinase 1 (ALPK1). ALPK1 is an intracytoplasmic serine threonine protein kinase that plays an important role in activating the innate immune response to bacteria via TRAF-interacting protein with forkhead-associated domain (TIFA) dependent proinflammatory NF-κB signaling .
    ALPK1-IN-1
  • HY-100746
    STF-62247
    1 Publications Verification

    		 Autophagy Cancer
    STF-62247 is an autophagy inducer that selectively cytotoxic to VHL-deficient renal cell carcinoma (IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively) .
    STF-62247
  • HY-146052
    Autophagy inducer 3

    		Atg8/LC3 Autophagy Cancer
    Autophagy inducer 3 has autophagy induced activity. Autophagy inducer 3 possesses robust autophagic cell death in diverse cancer cells sparing normal counterpart. Autophagy inducer 3 induces lethal autophagy by formation of characteristic autophagic vacuoles, LC3 puncta formation, upregulation of signature autophagy markers like Beclin and Atg family proteins .
    Autophagy inducer 3

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