2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. ω-Conotoxin CVIB

ω-Conotoxin CVIB is a non-selective N- and P/Q-type voltage-gated calcium channels (VGCCs) antagonist. ω-Conotoxin CVIB inhibits depolarization-activated whole-cell VGCC currents in dorsal root ganglion (DRG) neurons with a pIC50 of 7.64.

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ω-Conotoxin CVIB Chemical Structure

ω-Conotoxin CVIB Chemical Structure

CAS No. : 325164-09-8

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ω-Conotoxin CVIB Related Antibodies

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Description

ω-Conotoxin CVIB is a non-selective N- and P/Q-type voltage-gated calcium channels (VGCCs) antagonist. ω-Conotoxin CVIB inhibits depolarization-activated whole-cell VGCC currents in dorsal root ganglion (DRG) neurons with a pIC50 of 7.64[1].

Molecular Weight

2710.18

Formula

C102H173N41O32S7
CAS No.
Sequence

Cys-Lys-Gly-Lys-Gly-Ala-Ser-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Arg-Gly-Ser-Cys-Arg-Ser-Gly-Arg-Cys-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20, Cys15-Cys25)
Sequence Shortening

CKGKGASCRKTMYDCCRGSCRSGRC-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20, Cys15-Cys25)
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ω-Conotoxin CVIB Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ω-Conotoxin CVIB325164-09-8Sodium ChannelNa channelsNa+ channelsN- and P/Q-type voltage-gated calcium channelsInhibitorinhibitorinhibit

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ω-Conotoxin CVIB
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