1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. Calcium Channel
  3. ω-Conotoxin CVIF

ω-Conotoxin CVIF is a selective Cav2.2 channel inhibitor with an IC50 of 34.3 nM in rat isolated DRG neurons. ω-Conotoxin CVIF block of Cav2.2 channels is weakly reversible.

For research use only. We do not sell to patients.

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ω-Conotoxin CVIF Chemical Structure

ω-Conotoxin CVIF Chemical Structure

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Description

ω-Conotoxin CVIF is a selective Cav2.2 channel inhibitor with an IC50 of 34.3 nM in rat isolated DRG neurons. ω-Conotoxin CVIF block of Cav2.2 channels is weakly reversible[1].

IC50 & Target

IC50: 34.3 nM (Cav2.2 in rat isolated DRG neurons)[1]

Molecular Weight

2665.07

Formula

C101H170N40O33S6

Sequence

Cys-Lys-Gly-Lys-Gly-Ala-Ser-Cys-Arg-Arg-Thr-Ser-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Leu-Gly-Arg-Cys-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20 and Cys15-Cys27)

Sequence Shortening

CKGKGASCRRTSYDCCTGSCRLGRC-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20 and Cys15-Cys27)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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ω-Conotoxin CVIF Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
ω-Conotoxin CVIF
Cat. No.:
HY-P5804
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