1. Metabolic Enzyme/Protease Immunology/Inflammation
  2. Cytochrome P450 NO Synthase
  3. 7-Ethoxyresorufin

7-Ethoxyresorufin  (Synonyms: Resorufin ethyl ether)

Cat. No.: HY-D0145 Purity: 99.61%
SDS COA Handling Instructions Technical Support

7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase.

For research use only. We do not sell to patients.

7-Ethoxyresorufin Chemical Structure

7-Ethoxyresorufin Chemical Structure

CAS No. : 5725-91-7

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO In-stock
Solid
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 7-Ethoxyresorufin:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE 7-Ethoxyresorufin

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2][3][4].

IC50 & Target

CYP1

 

In Vitro

7-Ethoxyresorufin (2 μM, 10-15 min) reduces the relaxant actions of acetylcholine (0.01-10 μM) in endothelium-intact rings and of NO (0.3-10 M), GTN (0.01-10 μM) and SNP (0.01-10 μM) in endothelium-denuded rings in concentration-dependent manners in rat aortic rings[1].
7-Ethoxyresorufin (2.5, 5.0 and 10 μM, 2 h) reacts with NADPH in the presence of acid with the formation of a product which fluoresces at the same wavelength as Resorufin (HY-123533)[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

241.24

Formula

C14H11NO3

CAS No.
Appearance

Solid

Color

Orange to red

Emission (Em)

460

Excitation (Ex)

335

SMILES

O=C1C=CC2=NC3=C(C=C(OCC)C=C3)OC2=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMF : 2 mg/mL (8.29 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1452 mL 20.7262 mL 41.4525 mL
5 mM 0.8290 mL 4.1452 mL 8.2905 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.61%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF 1 mM 4.1452 mL 20.7262 mL 41.4525 mL 103.6312 mL
5 mM 0.8290 mL 4.1452 mL 8.2905 mL 20.7262 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
7-Ethoxyresorufin
Cat. No.:
HY-D0145
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