1. Dye Reagents
  2. Dansylcadaverine

Dansylcadaverine (Synonyms: Monodansyl cadaverine)

Cat. No.: HY-D1027 Purity: 98.00%
Handling Instructions

Dansylcadaverine is a fluorescent probe.

For research use only. We do not sell to patients.

Dansylcadaverine Chemical Structure

Dansylcadaverine Chemical Structure

CAS No. : 10121-91-2

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References


Dansylcadaverine is a fluorescent probe.

In Vitro

Detection of Dansylcadaverine fluorescence after SDS-PAGE shows that the amount of actin-thymosin β4 crosslink is very low in the presence of Dansylcadaverine and transglutaminase, while there are large amounts of Dansylcadaverine-labeled thymosin β4 and actin. The amount of cross-link further decreases in the presence of Dansylcadaverine competing for Lys residues of either G-actin or thymosin β4 (100 μM). In the absence of thymosin β4, Dansylcadaverine-labeled actin polymerized to F-actin as revealed by fluorescence detection after native PAGE[1].


-20°C, protect from light, stored under nitrogen

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (186.31 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9810 mL 14.9049 mL 29.8098 mL
5 mM 0.5962 mL 2.9810 mL 5.9620 mL
10 mM 0.2981 mL 1.4905 mL 2.9810 mL
*Please refer to the solubility information to select the appropriate solvent.
Kinase Assay

To determine the time course of transglutamination, thymosin β4 (120 μM) is incubated with Dansylcadaverine (5 mM) in 70 μL buffer consisting of 10 mM Tris-HCl, pH 7.4, 15 mM CaCl2, 3 mM DTT. The reaction is started by addition of 0.1 U transglutaminase. Immediately after addition of the enzyme (t=0) and at indicated times,10 μL are taken from the mixture, diluted in 490 μL 0.1% TFA to stop the reaction and analyzed by HPLC[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Assay

MCF7 cells (2.4×104) are seeded into 35 mm plates. After 24 h incubation, CuO NPs are added with an increasing concentration in the presence or absence of 3-Methyladenine (3-MA) for different time periods . The cells are then incubated with 50 mM Dansylcadaverine (MDC) at 37°C for 15 min and washed with 1×PBS three times with 5 min interval. Finally, the cells are observed under a fluorescence microscope[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight









Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Cat. No.: HY-D1027