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- Liliaceae
- Fritillaria pallidiflora Schrenk ex Fisch. & C. A. Mey.
Fritillaria pallidiflora Schrenk ex Fisch. & C. A. Mey.
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Fritillaria pallidiflora Schrenk ex Fisch. & C. A. Mey. (5)
- Formula: C27H45NO3
- Molecular Weight: 431.65
Isoverticine, a bioactive isosteroidal alkaloid isolated from bulbus of Fritillaria pallidiflora, displays significant cytotoxicity.
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- Formula: C33H53NO8
- Molecular Weight: 591.78
Imperialine 3-β-D-glucoside is the glycoside of Imperialine (HY-N0696). Imperialine 3-β-D-glucoside may exhibit anti-tumor properties against multi-agent resistant tumor cells.
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- Formula: C45H74O18
- Molecular Weight: 903.07
Protobioside is a steroidal saponin found in the dry bulbs of Fritillaria pallidiflora Schrenk. Protobioside shows no significant cytotoxic activity against human cancer cells.
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- Formula: C27H43NO2
- Molecular Weight: 413.64
Chuanbeinone (22-Epidelavinone) is an orally active alkaloid found in Fritillaria pallidiflora. Chuanbeinone shows cytotoxicity against mutiple cancer cells and can induces apoptosis and S phase arrest. Chuanbeinone downregulates Bcl-2, upregulates Bax, and activates caspase-3. Chuanbeinone exerts anti-inflammatory and antitussive effects by reducing pro-inflammatory cytokine (IL-1β, IL-6 and TNF-α) production and mRNA expression, and inhibiting TRIF-, MyD88-, NF-κB-, and MAPK-dependent signaling pathways. Chuanbeinone inhibits AChE and BChE with IC50 values of 7.7 and 0.7 μM. Chuanbeinone can be used for the researches of lung carcinoma, cough, inflammatory diseases.
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- Formula: C27H43NO2
- Molecular Weight: 413.64
Delavinone (Sinpeinine A) is an alkaloid. Delavinone is suitable for electrospray ionization (ESI) positive electrode detection.
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