2. Natural Products
  3. Disease Research Fields Plants Alkaloids Steroids
  4. Liliaceae Cancer Piperidine Alkaloids
  5.  Fritillaria monantha Migo Fritillaria pallidiflora
  6. Isoverticine

Isoverticine, a bioactive isosteroidal alkaloid isolated from bulbus of Fritillaria pallidiflora, displays significant cytotoxicity.

For research use only. We do not sell to patients.

Isoverticine Chemical Structure

Isoverticine Chemical Structure

CAS No. : 23496-43-7

Size Price Stock Quantity
1 mg USD 130 In-stock
5 mg USD 270 In-stock
10 mg USD 450 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Isoverticine Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Isoverticine, a bioactive isosteroidal alkaloid isolated from bulbus of Fritillaria pallidiflora, displays significant cytotoxicity[1].

In Vitro

Isoverticine displays cytotoxicity, with IC50s of 49.56, 31.63, 61.91 and 108.8 µg/mL, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Isoverticine Related Antibodies
Molecular Weight

431.65

Formula

C27H45NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]([C@]1([H])C[C@H]2O)(CC2)[C@]3([H])[C@](C[C@H]1O)([H])[C@@](CC[C@@]4([H])[C@@]5([H])CN(C[C@H]6C)[C@](CC6)([H])[C@@](O)4C)([H])[C@@]5([H])C3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (231.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3167 mL 11.5835 mL 23.1669 mL
5 mM 0.4633 mL 2.3167 mL 4.6334 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3167 mL 11.5835 mL 23.1669 mL 57.9173 mL
5 mM 0.4633 mL 2.3167 mL 4.6334 mL 11.5835 mL
10 mM 0.2317 mL 1.1583 mL 2.3167 mL 5.7917 mL
15 mM 0.1544 mL 0.7722 mL 1.5445 mL 3.8612 mL
20 mM 0.1158 mL 0.5792 mL 1.1583 mL 2.8959 mL
25 mM 0.0927 mL 0.4633 mL 0.9267 mL 2.3167 mL
30 mM 0.0772 mL 0.3861 mL 0.7722 mL 1.9306 mL
40 mM 0.0579 mL 0.2896 mL 0.5792 mL 1.4479 mL
50 mM 0.0463 mL 0.2317 mL 0.4633 mL 1.1583 mL
60 mM 0.0386 mL 0.1931 mL 0.3861 mL 0.9653 mL
80 mM 0.0290 mL 0.1448 mL 0.2896 mL 0.7240 mL
100 mM 0.0232 mL 0.1158 mL 0.2317 mL 0.5792 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isoverticine23496-43-7OthersisosteroidalalkaloidcytotoxicityantitumorInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Isoverticine
Cat. No.:
HY-N7596
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.