2. Natural Products
  3. Plants
  4. Leguminosae
  5. Glycyrrhiza glabra Linn.

Glycyrrhiza glabra Linn.

Glycyrrhiza glabra Linn. (18):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N6911A
    18α-Glycyrrhizic acid 83896-44-0 99.90%
    18α-Glycyrrhizic acid is a derivate of Glycyrrhizic acid. 18α-Glycyrrhizic acid has weak antihepatotoxic anti-inflammatory activities.
    18α-Glycyrrhizic acid
  • HY-186188
    Licoagrocarpin 202815-29-0
    Licoagrocarpin is an isoprenylated pterocarpan, a type of naturally occurring flavonoid found in the roots of Glycyrrhiza glabra. Licoagrocarpin serves as a precursor in the biosynthetic pathway of Glabridin (HY-N0393).
    Licoagrocarpin
  • HY-N19837
    Kanzonol Y 184584-87-0
    Kanzonol Y is a chalcone compound that can be found in the roots of Glycyrrhiza glabra. Kanzonol Y exerts anticancer and anti-dengue virus activity.
    Kanzonol Y
  • HY-N19818
    Glycybridin C 2088505-67-1
    Glycybridin C is a Protein tyrosine phosphatase 1B (PTP1B) inhibitor and pregnane X receptor (PXR) ligand. Glycybridin C inhibits insulin and leptin signaling pathway negative regulation, LPS (HY-D1056)-induced NF-κB transcriptional activity. Glycybridin C forms hydrophobic and π-π stacking interactions with Met243, Phe288, Tyr306, and His407 residues of PXR. Glycybridin C can be used for the research of hepatocellular carcinoma, colorectal adenocarcinoma, breast carcinoma.
    Glycybridin C
  • HY-N11846
    4′-O-Methylglabridin 68978-09-6
    4′-O-Methylglabridin is an apoptosis inducer with antioxidant, cell cycle-disrupting and anticancer cytotoxic activities. 4′-O-Methylglabridin inhibits various cancer cell lines including liver cancer, breast cancer and colorectal cancer cell lines. By reducing the expression levels of phosphorylated Rb (Ser807/811) and p21 proteins, 4′-O-Methylglabridin promotes cell accumulation at the subG1 and G2/M phases, and triggers caspase-dependent apoptosis via cytochrome C release and caspase-9 activation. 4′-O-Methylglabridin also exerts antioxidant effects by inhibiting lipid peroxide levels and reducing β-carotene consumption, thereby blocking LDL oxidation. 4′-O-Methylglabridin can be used in the research of various cancers and atherosclerotic diseases.
    4′-O-Methylglabridin
  • HY-N18007
    3-Hydroxyglabrol 74148-41-7
    3-Hydroxyglabrol is an Antibacterial agent. 3-Hydroxyglabrol can be isolated from Glycyrrhiza glabra L. var. typica. 3-Hydroxyglabrol inhibits the growth of Staphylococcus aureus (ATCC 13709) and Mycobacterium smegmatis (ATCC 607), with a MIC of 6.25 mcg/mL. 3-Hydroxyglabrol can be used for the research of Staphylococcus aureus infection, Mycobacterium smegmatis infection.
    3-Hydroxyglabrol
  • HY-W1053643
    3,3',5'-Trihydroxy-4-methoxybibenzyl 60640-97-3
    3,3',5'-Trihydroxy-4-methoxybibenzyl is a dihydrostilbene derivative that can be found in the leaves of Glycyrrhiza glabra.
    3,3',5'-Trihydroxy-4-methoxybibenzyl
  • HY-N13820
    Liquiridiolic acid 20528-70-5
    Liquiridiolic acid is a natural triterpene.
    Liquiridiolic acid
  • HY-N12385
    Hispaglabridin B 68978-02-9
    Hispaglabridin B is an anti-oxidant agent that can be isolated from Glycyrrhiza glabra. Hispaglabridin B exhibits potent peroxynitrite scavenging activity with an IC50 of 3.2 μM, and shows activity in a low-density lipoprotein (LDL) oxidation system. Hispaglabridin B is also a FoxO1 inhibitor. Hispaglabridin B improves muscle wasting by inhibiting catabolism in vivo and in vitro.
    Hispaglabridin B
  • HY-N3744
    Dihydrocitflavanone 70897-14-2
    Dihydrocitflavanone is a natural flavonoid.
    Dihydrocitflavanone
  • HY-N11976
    Glycyrrhizin-6′′-methylester 1186016-30-7
    Glycyrrhizin-6′′-methylester (compound 22) is a glycyrrhizin that can be isolated from licorice root. Glycyrrhizin-6′′-methylester can participate as an aglycone in the formation of methyl glucuronate, producing a sweet and licorice taste, but no bitterness. This reveals the importance of the free carboxyl group on the glycoside cone-bound glucuronic acid for natural sweetness and licorice taste.
    Glycyrrhizin-6′′-methylester
  • HY-N12289
    Kanzonol D 155233-20-8
    Kanzonol D is a flavonoid compound that can be found in the hairy root cultures of Glycyrrhiza glabra.
    Kanzonol D
  • HY-142100
    Licoagrochalcone C 325144-68-1
    Licoagrochalcone C, a flavonoid, reveals efficacious inhibitory activity on NF-κB transcription. Licoagrochalcone C shows significant inhibitory activity on LPS (HY-D1056)-induced NO production.
    Licoagrochalcone C
  • HY-N19004
    Glyasperin M 156162-05-9
    Glyasperin M is an isoflavanone found in Glycyrrhiza aspera.
    Glyasperin M
  • HY-W588272
    cis-Linalool oxide 5989-33-3
    cis-Linalool oxide is a monoterpenoid compound with an aromatic odor, and is often used as a flavoring agent. It is commonly found in certain species of aromatic plants.
    cis-Linalool oxide
  • HY-114693
    Licoagrochalcone B 325144-67-0
    Licoagrochalcone B is a prenylated retrochalcone that can be found in Glycyrrhiza glabra hairy root cultures.
    Licoagrochalcone B
  • HY-125597
    Glabrocoumarone A 178330-48-8
    Glabrocoumarone A (Kanzonol U) is a coumarin identified from G. glabra.
    Glabrocoumarone A
  • HY-N10133
    Licoflavanone 119240-82-3
    Licoflavanone (3′-Prenylnaringenin) is a flavanone with antioxidant, anti-inflammatory and anticancer activities. Licoflavanone can be isolated from the leaf extract of Glycyrrhiza glabra. Licoflavanone downregulates the mTOR/PI3K/AKT signaling pathway to inhibit the proliferation, migration and invasion of cancer cells, while activates Bax, Bad and multiple caspase enzymes to induce apoptosis. Its anti-inflammatory effect is manifested by reducing the nuclear translocation of NF-κB, decreasing the phosphorylation levels of p38, JNK and ERK1/2, thereby inhibiting the expression of nitric oxide, proinflammatory cytokines, COX-2 and iNOS. Licoflavanone is used in studies on nasopharyngeal carcinoma and related mechanisms.
    Licoflavanone