- Natural Products
- Plants
- Cephalotaxaceae
- Cephalotaxus harringtonia
Cephalotaxus harringtonia
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Cephalotaxus harringtonia (2)
- Formula: C19H18O4
- Molecular Weight: 310.34
Harringtonolide is a potent RACK1 inhibitor (IC50=39.66 μM in A375 cells). Harringtonolide inhibits the epithelial-mesenchymal transition (EMT) process and cell proliferation by affecting the interaction between FAK and RACK1. Harringtonolide has plant growth inhibitory, antiviral, anti-inflammatory, and antiproliferation activities.
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- Formula: C18H21NO5
- Molecular Weight: 331.36
11-Hydroxycephalotaxine (Compound 1a) is a cephalotaxus alkaloid that can be isolated from Cephalotaxus species.
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