Vaccaria segetalis (Neck.) Garcke
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Vaccaria segetalis (Neck.) Garcke (3)
- Formula: C24H32N6O5
- Molecular Weight: 484.55
Segetalin B, an orally active cyclopentapeptide found in Vaccaria segetalis, possesses estrogen-like activity. Segetalin B promotes mineralization of ovariectomized rat-derived bone marrow mesenchymal stem cells (BMSCs) in vitro and increases the level of osteocalcin, BMP-2, ALP, and SIRT1 activity. Segetalin B is promising for research of post-menopausal osteoporosis (PMOP).
- Formula: C27H30O15
- Molecular Weight: 594.52
Isosaponarin is a flavone glycoside isolated from wasabi leaves. Isosaponarin is a P4HA2 enzymatic agonist. Isosaponarin increases collagen synthesis via up-regulated TGF-β type II receptor (TβR-II) and prolyl 4-hydroxylase (P4H) proteins production, promoting skin health and wound healing. Isosaponarin-rich plants exhibit strong antimicrobial, antioxidant, anti-hyaluronidase, antiplatelet, anti-atopic dermatitis, and anti-tumor effects.
- Formula: C42H48O22
- Molecular Weight: 904.82
Vaccarin E is a natural C-glycosylflavone that could be isolated from V. hispanica.
