2. Signaling Pathways
  3. GPCR/G Protein
  4. EBI2/GPR183
  5. EBI2/GPR183 Antagonist

EBI2/GPR183 Antagonist

EBI2/GPR183 Antagonists (3):

Cat. No. Product Name Effect Purity
  • HY-12336
    NIBR189
    		Antagonist 99.41%
    NIBR189 is an EBI2 (Epstein-Barr virus-induced gene 2) antagonist. NIBR189 inhibits human and mouse EBI2 with IC50s of 11 and 16 nM, respectively. NIBR189 can be used for the research of autoimmune diseases.
  • HY-116814
    ML401
    		Antagonist 99.93%
    ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity.
  • HY-147222
    SAE-14
    		Antagonist 98.26%
    SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC50 value of 28.5 nM, can antagonize 7α, 25-OHC–induced calcium mobilization with IC50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice.