1. Signaling Pathways
  2. GPCR/G Protein
  3. LPL Receptor
  4. LPAR1 Isoform
  5. LPAR1 Antagonist

LPAR1 Antagonist

LPAR1 Antagonists (3):

Cat. No. Product Name Effect Purity
  • HY-16039
    Antagonist 99.72%
    AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively.
  • HY-15706
    H2L 5765834
    Antagonist 98.36%
    H2L 5765834 is an antagonist of lysophosphatidic acid receptors LPA1, LPA3, and LPA5, with IC50s of 94, 752, and 463 nM respectively.
  • HY-115450
    Antagonist 99.43%
    ONO-0300302 is an orally active and potent LPA1 (lysophosphatidic acid receptor 1) antagonist, with an IC50 of 0.086 μM. ONO-0300302 is a slow tight binding inhibitor, and its binding affinity increases with time, with Kd of 0.34 nM (37 °C, 2 h). ONO-0300302 can be used for benign prostatic hyperplasia (BPH) research.