1. GPCR/G Protein
  2. GCGR
  3. BI 456906

BI 456906 

Cat. No.: HY-P3470
Handling Instructions

BI 456906 is a dual-acting agonist of glucagon-like peptide 1 (GLP-1) receptor and glucagon receptor. BI 456906 can be used for the research of obesity and non-alcoholic steatohepatitis (NASH).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

BI 456906 Chemical Structure

BI 456906 Chemical Structure

CAS No. : 2477737-80-5

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Description

BI 456906 is a dual-acting agonist of glucagon-like peptide 1 (GLP-1) receptor and glucagon receptor. BI 456906 can be used for the research of obesity and non-alcoholic steatohepatitis (NASH)[1][2].

In Vitro

BI 456906 potentiates glucose-stimulated insulin secretion from rodent and perifused human islets and potently inhibits glycogen synthesis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

BI 456906 reduces food intake, gastric emptying, and improvements in oral glucose tolerance in dose-dependent in single administration to lean mice[2].
BI 456906 led to bodyweight-lowing in DIO mice[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Product Name:
BI 456906
Cat. No.:
HY-P3470
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