Protein kinase A (PKA)

Definition:

Protein kinase A (PKA), the Cyclic adenosine monophosphate (cAMP)-dependent protein kinase, is ubiquitously expressed in mammalian cells, can be activated in response to a plethora of biological stimuli, and phosphorylates more than 250 known substrates. PKA serves as the primary effector of the second-messenger molecule 3',5'-cyclic adenosine monophosphate (cAMP), has mostly inhibitory effects on the adaptive immune response. PKA has a wide range effects in energy homeostasis, memory formation and immunity.

References:

[1]. Thomas S Postler, et al. A most versatile kinase: The catalytic subunit of PKA in T-cell biology. Int Rev Cell Mol Biol. 2021;361:301-318. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.