The Bloom syndrome protein (BLM)

Definition:

The Bloom syndrome protein (BLM) is the gene defective in Bloom's syndrome. BLM encodes a 159-kDa protein possessing DNA-stimulated ATPase and ATP-dependent DNA helicase activities.

References:

[1]. R M Brosh Jr, et al. Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity. J Biol Chem. 2000 Aug 4;275(31):23500-8. [Content Brief]

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