2. NF-κB MAPK/ERK Pathway
  3. NF-κB p38 MAPK
  4. Chebulanin

Chebulanin, a polyphenol acid, exerts its anti-inflammatory and anti-arthritic effects via inhibiting NF-κB and MAPK activation in collagen-induced arthritis mice. Chebulanin inhibits the nuclear translocation of p38 and p65 in LPS-stimulated macrophages.

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Chebulanin Chemical Structure

Chebulanin Chemical Structure

CAS No. : 166833-80-3

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Chebulanin Related Antibodies

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Description

Chebulanin, a polyphenol acid, exerts its anti-inflammatory and anti-arthritic effects via inhibiting NF-κB and MAPK activation in collagen-induced arthritis mice. Chebulanin inhibits the nuclear translocation of p38 and p65 in LPS-stimulated macrophages[1].

Molecular Weight

652.47

Formula

C27H24O19
CAS No.
SMILES

OC(C[C@H](C(O[C@@]([C@H]1CO)([H])C2O)=O)[C@@]([C@@H]3O)([H])C(C(C(O[C@@]2([H])[C@@H](O1)OC(C(C=C4O)=CC(O)=C4O)=O)=O)=CC(O)=C5O)=C5OC3=O)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
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Chebulanin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chebulanin166833-80-3NF-κBp38 MAPKNuclear factor-κBNuclear factor-kappaBpolyphenol acidanti-inflammatoryanti-arthriticarthritismacrophagesInhibitorinhibitorinhibit

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