2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. µ-Conotoxin KIIIA TFA

μ-Conotoxin KIIIA TFA is an analgesic μ-conotoxin that can be isolated from Conus kinoshitai. μ-Conotoxin KIIIA blocks mammalian neuronal voltage-gated sodium channels (VGSCs) (Nav1.2). μ-Conotoxin KIIIA TFA can be used for research of pain.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

µ-Conotoxin KIIIA TFA Chemical Structure

µ-Conotoxin KIIIA TFA Chemical Structure

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µ-Conotoxin KIIIA TFA Related Antibodies

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Description

μ-Conotoxin KIIIA TFA is an analgesic μ-conotoxin that can be isolated from Conus kinoshitai. μ-Conotoxin KIIIA blocks mammalian neuronal voltage-gated sodium channels (VGSCs) (Nav1.2). μ-Conotoxin KIIIA TFA can be used for research of pain[1][2].

Molecular Weight

1884.16 (free base)

Formula

C70H106N28O22S6.xC2HF3O2
Appearance

Solid

Color

White to off-white

Sequence

Cys-Cys-Asn-Cys-Ser-Ser-Lys-Trp-Cys-Arg-Asp-His-Ser-Arg-Cys-Cys-NH2 (Disulfide bonds: Cys1-Cys9,Cys2-Cys15,Cys4-Cys16)
Sequence Shortening

CCNCSSKWCRDHSRCC-NH2 (Disulfide bonds: Cys1-Cys9,Cys2-Cys15,Cys4-Cys16)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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This equation is commonly abbreviated as: C1V1 = C2V2

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
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µ-Conotoxin KIIIA TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

µ-Conotoxin KIIIASodium ChannelNa channelsNa+ channelsConotoxintoxinneuronalpainanalgesicInhibitorinhibitorinhibit

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