CD39 Protein, Human (Baculovirus, His)

The CD39 protein is an important regulator in the nervous system, coordinating purinergic neurotransmission by hydrolyzing ATP and other nucleotides. Its enzymatic ability can hydrolyze platelet-activated ADP into AMP, thereby effectively preventing platelet aggregation. CD39 Protein, Human (Baculovirus, His) is the recombinant human-derived CD39 protein, expressed by Sf9 insect cells , with C-6*His labeled tag. The total length of CD39 Protein, Human (Baculovirus, His) is 441 a.a., with molecular weight of ~60 kDa.

In the nervous system, the CD39 protein serves as a key regulator of purinergic neurotransmission by hydrolyzing ATP and other nucleotides. Its enzymatic activity extends to the prevention of platelet aggregation, as it efficiently hydrolyzes platelet-activating ADP to AMP. Notably, CD39 exhibits equal proficiency in the hydrolysis of both ATP and ADP, emphasizing its versatile role in modulating purinergic signaling pathways and contributing to the intricate regulation of neurotransmission and platelet function.

Human

Sf9 insect cells

C-6*His

P49961 (T38-V478)

953  [NCBI]

TQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLGKFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTKRFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAFSAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQPLSTPLSHSTYV

Approximately 60 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.