Bdkrb2 - bradykinin receptor, beta 2 Gene

Mus musculus

Also known as B2; B2R; BK2; B(2); BK-2; BK2R; BKR2; BRB2

Gene ID: 12062 | Gene type: protein coding

About Bdkrb2

Chromosome 12: 105,529,485-105,561,496 forward strand.GRCm39:CM001005.3

This gene has 1 transcript (splice variant), 362 orthologues, 9 paralogues and is associated with 27 phenotypes.

Summary

Predicted to enable several functions, including G protein-coupled receptor binding activity; Bradykinin Receptor activity; and protein heterodimerization activity. Acts upstream of or within several processes, including negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator; negative regulation of peptidyl-serine phosphorylation; and vasodilation. Predicted to be located in Golgi apparatus and endosome. Predicted to be active in plasma membrane. Is expressed in collecting duct and metanephros. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; hypertension; and rhinitis. Orthologous to human BDKRB2 (Bradykinin Receptor B2). [provided by Alliance of Genome Resources, Apr 2022]

Bdkrb2 Products(1)

mRNA	Protein	Name
NM_009747.2	NP_033877.3	B2 bradykinin receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS01457	BDKRB2 Human Pre-designed siRNA Set A	/	Unkown
HY-RS01458	Bdkrb2 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS01459	Bdkrb2 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Bdkrb2	NCBI	NCBI:624

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