2. Gene
  3. RDM1 - RAD52 motif containing 1 Gene

RDM1 - RAD52 motif containing 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RAD52B

Gene ID: 201299 | Gene type: protein coding

About RDM1

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:35,918,080-35,930,773 (from NCBI)

This gene has 14 transcripts (splice variants), 1 gene allele and 193 orthologues. Biased expression in testis (RPKM 2.2), lymph node (RPKM 0.3) and 5 other tissues.

Summary

This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported. [provided by RefSeq, Jul 2008]

RDM1 Products(9)

mRNA Protein Name
NM_001034836.2 NP_001030008.1 RAD52 motif-containing protein 1 isoform 2
NM_001163120.2 NP_001156592.1 RAD52 motif-containing protein 1 isoform 3
NM_001163121.2 NP_001156593.1 RAD52 motif-containing protein 1 isoform 4
NM_001163122.1 NP_001156594.1 RAD52 motif-containing protein 1 isoform 5
NM_001163124.1 NP_001156596.1 RAD52 motif-containing protein 1 isoform 6
NM_001163125.1 NP_001156597.1 RAD52 motif-containing protein 1 isoform 7
NM_001163130.1 NP_001156602.1 RAD52 motif-containing protein 1 isoform 8
NM_001330194.2 NP_001317123.1 RAD52 motif-containing protein 1 isoform 9
NM_145654.4 NP_663629.1 RAD52 motif-containing protein 1 isoform 1

RDM1 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (32 - 88)

Rad52_Rad22

Rad52_Rad22: Rad52/22 family double-strand break repair protein (92 - 210)

  • 0
  • 100
  • 200
  • 284 a.a.
Protein Preferred Names Protein Names

RAD52 motif-containing protein 1

RAD52 homolog B

Related Diseases

Diseases Alias
Plummer'S Disease

Toxic Nodular Goiter

Plummer Disease

Goiter Toxic Nodular
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11805 RDM1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RDM1 RGD RGD:1310432
Macaca mulatta RDM1 VGNC VGNC:76778
Bos taurus RDM1 VGNC VGNC:33844
Mus musculus RDM1 MGD MGI:1913849