CDC42EP4 - CDC42 effector protein 4 Gene

Homo sapiens

Also known as CEP4; BORG4; KAIA1777

Gene ID: 23580 | Gene type: protein coding

About CDC42EP4

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:73,283,624-73,312,001 (from NCBI)

This gene has 9 transcripts (splice variants), 238 orthologues and 5 paralogues. Ubiquitous expression in ovary (RPKM 35.1), brain (RPKM 34.5) and 25 other tissues.

Summary

The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin Cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008]

CDC42EP4 Products(1)

mRNA	Protein	Name
NM_012121.5	NP_036253.2	cdc42 effector protein 4

CDC42EP4 Protein Structure

PBD

BORG_CEP

0
100
200
300
356 a.a.

Protein Preferred Names

Protein Names

cdc42 effector protein 4

CDC42 effector protein (Rho GTPase binding) 4

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02305	CDC42EP4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CDC42EP4	RGD	RGD:1311567
Bos taurus	CDC42EP4	VGNC	VGNC:27075
Felis catus	CDC42EP4	VGNC	VGNC:98786
Canis familiaris	CDC42EP4	VGNC	VGNC:39003
Macaca mulatta	CDC42EP4	VGNC	VGNC:70789
Mus musculus	CDC42EP4	MGD	MGI:1929760

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