2. Gene
  3. Htr1a - 5-hydroxytryptamine receptor 1A Gene

Htr1a - 5-hydroxytryptamine receptor 1A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as 5HT1A; RAT5HT1A

Gene ID: 24473 | Gene type: protein coding

About Htr1a

Primary_assembly 2: 36,694,174-36,695,442 forward strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 66 orthologues, 8 paralogues and is associated with 21 phenotypes.

Summary

Enables several functions, including G protein-coupled serotonin receptor activity; G-protein alpha-subunit binding activity; and serotonin binding activity. Involved in several processes, including NMDA glutamate receptor clustering; adenylate cyclase-inhibiting serotonin receptor signaling pathway; and regulation of secretion. Located in axon hillock. Is active in GABA-ergic synapse. Is integral component of presynaptic membrane. Used to study Parkinson's disease and panic disorder. Human ortholog(s) of this gene implicated in anxiety disorder; mental depression; and panic disorder. Orthologous to human HTR1A (5-hydroxytryptamine receptor 1A). [provided by Alliance of Genome Resources, Apr 2022]

Htr1a Products(1)

mRNA Protein Name
NM_012585.2 NP_036717.2 5-hydroxytryptamine receptor 1A
Protein Preferred Names Protein Names

5-hydroxytryptamine receptor 1A

5-HT-1A

5-HT1A

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

serotonin 1A receptor

serotonin 5-HT1A receptor

serotonin receptor 1A

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06458 HTR1A Human Pre-designed siRNA Set A / Unkown
HY-RS06459 Htr1a Mouse Pre-designed siRNA Set A / Unkown
HY-RS06460 Htr1a Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Htr1a NCBI NCBI:3350